Castilian: Nail of cat, pothook, rattan of water, hit, rangaya, damento, paotali, Unganangi.
English: cat's claw
Spanish: Nail of cat, pothook, rattan of water, hit, rangaya, damento, paotali, Unganangi.
French: griffe du chat
English: cat's claw
Alkaloids: they have been gotten to isolate up to 6 alkaloids of the oxindólico type emphasizing the pteropodina (Isomeric A) and the rynchofilina vegetal Steroids: beta-sitosterol, estigmasterol, campesterol, Polifenoles and triterpenoides
Contraindications: Trustworthy data of their toxicity are not known until the moment, although the applications made in diverse subjects to high doses have not even detected indirect effect
Commentary
According to a South American missionary, it was an effective remedy against the cancer, specially the lung cancer. The cat nail was known centuries ago by the Aguaruna, the Bora, the Ashánika, the Conibo, the Pior, the Shipibo and the Mashiguenga, all of them indigenous communities of Peru.
Between the preColombian towns a plant is considered magical and very healthful. They use the crust of the stems to cure digestive tumors, problems, infections and arthritis. For it they boil the crust until obtaining a very bitter liquid, although also they make macerations in water and alcohol.
The Ashánicas uses the leaves against the allergies. It is demonstrated that in these treatments efiacia arrives as of the 5 days. In arthritic pains about three months. It is plant of general use between the farmers and in Lima, the capital of Peru, is in the pharmacies.
The Nail of cat belongs to the family of the rubiáceas. One grows up in altitudes that go of the 600 to the 1,000 meters.
Taken care of with confusing it with other varieties that receive the same vulgar name, by which thing I recommend to ask for it by its scientific name: Tomentosa Uncaria. The spinosa Onosis, that is of the leguminosas ones was commercialized in Spain like Nail of cat, of very diuréticos effects. The Carpobrotus edulis is a cactaceous one that also is called vulgarly cat nail, with the particularitity to have anticancerigenic properties.
In Peru one has prohibited its harvesting and commercialization by its root, thing that seems me well, to protect to the species of the speculators and vandals. The crust is extracted of the stems that are cut over 1 meter on the ground. After this operation the liana regenerates to the 4 years. The Nail of cat is also cultivated in breeding grounds, although never it gets to be just like the wild varieties.
1952: Raymond-Hayer identifies an alkaloid in the leaves of the uncaria guianensis, the rincofilina.
1967: In the Institute of Pharmaceutical Biology of the University of Munich, by means of the Brand method compreba the inmunoestimulante action of the extracts of the tomentosa Uncaria. It was modified by Tympner in 1978
1974: Phillipson and the Hemingways discover in the leaves of the Uncaria guianensis and in the tomentosa Uncaria, the iso-rincofilina, and the alkaloids mitrafilina, dihidrocorinanteína, uncarina, hirsuteína. The isomitrafilina only was in tomentosa the Uncaria variety.
1976: Óscar Schuler takes to Rome, to the Department of Pharmacology of the University of San Marcos the content of alcaoides for its corresponding analysis. And it did it by a very special reason: a terminal cancer had been cured taking the tisane from nail of cat to newspaper during 6 months. Doctor Montenegro de Matta and her team of following investigators found alcaliodes in the sample: pteropodina, isopteropodina, speciofilina, iso-mitrafilina and unacarina F. As it did not convince to them nor believed it sufficient to cure a terminal cancer looked for other active principles and between polifenoles they found: epicatequina, procianidinas To, B1, B2, B4.
In the U.S.A. Klaus Keplinger it patented six isolated oxindólicos alkaloids by the root of tomentosa Uncaria. Its number of patent is: 4.844.901/4 julio/89. They are considered stimulating of the immunity, specially isopteropodina-A
From the Nail of cat they have been gotten to isolate more than 50 active principles, between which they emphasize the oxindólicos glicósidos ones of quinóvico acid (a derivative of ursólico acid with carboxilos in carbons 14 and 17), the characteristic triterpenos, tannins, alkaloids and esteroles (sitosterol, estigmasterol, campesterol). Between the pentacíclicos oxindólicos alkaloids we have: mitrafilina, isomitrafilina, pteropodina, isopteropodina, rincofilina, isorincofilina. If we examined the polihidroxilados tripertenos we found: acid 3 -, 6 -, 19-trihidroxi-urs-in-oico 13; acid 23-nor-24-oxometilen-3 -, 6 -, 19 -- trihidroxi-urs-12-in-18-oico 15. Between polifenoles we found derivatives of the epicatequina and the procianidinas To, B1, B, B4. The alkaloids were isolated mainly by Wagner and its collaborators, whereas the glucósidos ones of quinóvico acid, the tripertenos and polifenoles were isolated by Aquino and their collaborators.
1978 Tympner modifies the thesis of the Brand method such, consisting of the provoking attack to lincofitos by means of leavenings -; the quimioluminiscencia method - subsequent to the fagocitosis in lymphocytes that become fluorescent.
1984: Kreutzkamp Barbarian publicly presents/displays the results on her theses in Munich. Barbarian had found in the tomentosa Uncaria active principles of low molecular weight with inmunoestimulantes effects.
1985: Keplinger and its collaborators investigate the inmunoestimulante effect mentioned and the possible interference with the human eritrocitos previously, with different bacteria. During that observation they discover antiinflammatory effects that they attribute to the oxindólicos alkaloids. Nevertheless who has studied more, in Munich, the detailed effects of these alkaloids are Hildebert Wagner, that counts on investigations of bioensayos with enzymes and primary cellular cultures. It is in this year that publishes the studies on the alkaloids and the multiplying effect in the fagocitosis. In Italy, in the cities of Salerno and Naples, the quinóvicos glucósidos ones study, the tripertenos and the tannins, people in charge of antiinflammatory, antiviral, mutágena and antimutágena, antitumorlike the action, etc.
1989: In the Peruvian Medicine University Cayetano Heredia, Frame Coast studies in mice the preventive effect of gastric ulcers due to stress thanks to the tomentosa Uncaria.
1992: From the 7 to the 12 of October of that same year a congress dedicated to the tomentosa Uncaria is celebrated in Salermo. They go investigating of diverse paises, Peruvian, Italian Germans and. The congress said with the following title: "I TRADITIONAL MEDICINE CONGRESS ITALO-PERUANO ANDEAN ANTONIO RAIMONDI". His president was Fernando Cabieses Molina, Peruvian and founder-director of the INMETRA (Traditional Medicine Institute) of Peru. Some impressions of interest were: according to A. Aquino and its collaborators the compounds of greater polarity are more active against RNA-virus encapsulations that against the nonencapsulations. Livia Bianchi of the Institute of General Pathology of the University of Pavia, exposed: the extracts of the tomentosa Unacaria fight the presence of free radicals, which explains its antitumorlike action, antiinflammatory and antimutágena. The tests had been made with 8-metoxisolareno (8-MOP) and stocks of Salmonella thyphymurinum (TA102) with atuda of ultra-violet rayses.
In Milan, Renato Rizzi, of the Department of Pharmacology, Quimioterapia and Medical Toxicología of the University, studied the antimutagénica action in tinkles of people smokers. The patients toamaron cat nail during 15 days, examining them to it she before tinkles it and after these 15 days. On the other hand to another group of smokers it was examined to them also tinkles it. The result of tinkles it in treated smokers always did not give tinkles positive, all the opposite of deal with tomentosa uncaria.
Giafranco Peluso, of the Institute of protein Boiquímica, demonstrated in Naples that the extracts of tomentosa Uncaria, inhibit clearly the proliferation of DNA-POLYMERASES, in special the alpha.
The main properties of the tomentosa Uncaria are:
Inmunoestimulante:ello must to the alkaloids isomitrafilina and pteropodina. It increases to the fagocítica activity of the neutrófilos granulocitos and macrophages, and stimulates the production of linfoquinas. It also increases the number of monocitos in active phases in the peripheral circulation, until in a 50%, at least after one week of treatment. The granulocitos increase in a 60% their fagocitario power (test of Brand with Zimosan particles) in the presence of extracts to the 0.01%. Alteration in the proliferation of lymphocytes T in normal conditions does not exist, perí that there is in increase in the presence of antigens. He is useful in cancer, AIDS, sistémica candidiasis, herpes several and sarcoma of Kaposi.
Antiinflamatoria:gracias to the quinóvicos glucósidos ones. A 15% superior to the indometacina. ütil in reumatoide arthritis, arthritis diverse, bursitis, reumas, lupus and fibromialgias.
Antiradicales libres:eficaz in inflammatory, cancerous processes, febrile states and in exhibition to ionizing radiations.
Antimutágena and citostática:acción due to the isorincofilina. It inhibits the DNA polymerases alpha. The mitosis of cells H,L are reduced, whereas those of the normal fibroblasts they are not altered. ütil in cancer, in alive, avoiding the metástasis.
Antiviral: specially against the ARN-virus encapsulations. Useful against the virus of genital AIDS HIV, herpes and herpes to zóster, refriados, sinusitis, otitis, virus of the vesicular estomatitis, conjuntivitis.
Decisive Desintoxicante and of tracto digestivo:Es very useful when they fail the conventional treatments in the disease of Crohn, diverticulitis, colitis, hemorroides, fistulas, gastritis, ulcers, intestinal parasites, alterations of the intestinal flora, anal dripping.
Antalérgica:útil in neurobromquitis, lupus.
Desentoxicante of toxins ambientales:eficaz in chronic fatigue, organic depression, acne.
Anafrodisíaca for the varones:útil in prostatitis, regulator of the mentrual, dismenorrea cycle. Nevertheless the dye of Uncaria is afrodisíaca not to undergo the maceration an elevated temperature, as it is the case in prepared others. The decocciones, then, have an opposite effect, that is to say, anafrodisíaco.
Antiagregante plaquetaria:debido to the rincofilina. It prevents cardiac apoplexy, attacks, hypertension, arteriosclerosis, trombosis, tromboflebitis, etc.
Protector of eritrocitos in front of toxics.
(special Gratefulness by the information to "FITOMÉDICA")
MORE ON THE CAT NAIL
Used part: The crust, the leaves and the root are used
The existence of two species of the Uncaria sort is reported in amazonía
Peruvian: The Uncaria Guianenses and the Uncaria Tomentosa.
The traditional medicine makes cancerous use of them for the treatment of the reumatismo, arthritis, inflammations, cirrhosis, tumors, diabetes, irregularities of the menstrual cycle, at the moment is being made studies of this plant in the treatment of AIDS, among others.
It is contraindicated for gestantes, since contraceptive properties are attributed to him to the leaves.
The Uncaria Tomentosa, is a liana, of 18-19 meters of height, grows in high forests with abundant solar light, to 500-600 mts. on the level of the sea, its fruits are brown, the primary leaves are of reddish brown color.
Of the chemical investigations Wagner and collaborator they reported the isolation of 6 pentacíclicos oxindólicos alkaloids that are:
The Isopteropodina, the Pteropodina, the Mitrafilina, the Isomitrafilina, the Rinchofilina and the Isorinchofilina.
The farmacológicos tests have demonstrated that the isolated alkaloids produce a great increase of fagocitosis (injurious elimination of bacteria or bodies).
The watery or etanólicos extracts present/display a citostática, contracéptica and antiinflammatory activity.
Still it is left much to know the Uncaria Tomentosa, but the popular use is every greater time, their properties spread widely in the press oral and written and still more in the clinical treatment of hundreds of people who give their testimony of the curativo effect that in them has produced.
They are known around 60 species of Uncaria world-wide level, mainly in countries of Asia and Africa, many of studied them, but that apparently does not have the properties that are attributed to the Peruvian species.
Forms of use:
Geriáticos infusion, cofoundation, wines, and capsules.
A small summary of the study of a Peruvian University:
THERAPEUTIC ACTIONS
We have described summarily the tests of laboratory made to demonstrate to the actions antinflamatoria and inmunoestimulante of the tomentosa Uncaria, all of them have a common bottom, the immunity, enough
complex, but for the intention of this theoretical work and with a didactic aim, we divided these terapeuticas actions in single two aspects:
1, Antiinflammatory action; and 2. Inmunoestimulante action.
1. The Antinflamatoria Action, proven in the Laboratory of Experimental Pharmacology, actually is confirmed by the use that has been occurring him for very many years and at the present time.
What inflammatory affections are: arthritis under its different forms, bursitis (shoulder), prostatitis, tonsilitis, várices, hemorroides, is to say a range of diseases in which the inflammation predominates.
In all the cases disappearance of the pain and swelling is obtained or at least diminution of its intensity. The duration of a treatment depends on the recovery that is observed, can be prolonged, without annoyances are pronounced neither indirect effect nor collateral.
By the expressed properties it could be taken advantage of in the treatment of organic upheavals geronto (person of the third age), among others, arthritis, osteoartritis, prostatitis and rheumatic and muscular incapacity, typical ailments of this stage of the life.
It is used in the most elementary form like cofoundation and more outpost, industrially, under different forms: capsules containing 250-280 mg of dust; it tinctures to 20% in alcohol of 65%, capsules and grageas containing 90 -
150 mg of liofilizado of the watery extract.
The cofoundation takes place in the following form: 20-30 g of crumbled crust, shaving or dust, places in deposit with a liter of potable water, is boiled during 15 minutes; it is strained and it cooled; one drinks two glasses
daily, one half an hour before the breakfast and another one half an hour before the lunch.
The indication for the dust capsules is of 1-3 daily; for liofilizado and the atomized one, 1 daily. For knowledge of the relation between dye, liofilizado or atomized dust and, necessary for its due one
administration a dye teaspoon is equivalent to the content of almost 4 capsules of dust or to a contained capsule 100mg of liofilizado or of atomized.
The liofilizado one is product of the following procedure: the dust of the crust of tomentosa Uncaria is put under water digestion purified, to 85ºC during 30 minutes; one filters; it concentrates to the emptiness and low temperature;
the filtrate is put under liofilización, in a special equipment, that congeals it to very low temperature and soon it sublimates the water to high emptiness; it leaves like remainder a hygroscopic dust that represents of the 6-10% of the used dust.
Is procedure used in the preparation of many medicinal products: also nutritional corticoids, antibiotics, serums, vaccines, etc. and.
The atomized one is product that follows the stages previous: digestion, filtration and concentration soon, in special equipment (Spry-drying) are atomized in hot airflow, leaving like remainder a similar dust the previous one. Is also procedure used in the nutritional industry in the preparation of instantaneous coffee, vegetal dust milk, colorantes, etc. As one sees the different forms from presentation vary in its content, but we are sure that do not run risk in their use, because the done toxicológicos animal studies assign an insignificant toxicity to him far from the expressed usual doses. Anyway the user fits his administration according to the result without undergoing collateral effect some.
2. Inmunoestimulante Action. - Since we have explained the stimulating action inmuno of the tomentosa Uncaria has been proven in vitro in the laboratory and in alive in experimentation animals parallelly it is applied in clinic and particular doctor's offices. Let us see first of what the mechanism of the immunity in the human sort consists: an initial barrier of defense as opposed to the aggression of strange agents exists in the blood constituted by white globules or leukocytes that after a microbial, slight attack or massive, it raises to his number sign that along with the fever on 37,5ºC denounces the beginning of an infection, soon rises one more second more aggressive and effective barrier constituted by monocellular elements, the lymphocytes T, calls today CD4, whose origin is
gland thymus; soon lymphocytes B, coming from the marrow, both are secretory of antibodies that annihilate and ingest the invader or prevent their proliferation. Of another side, the monocitos give rise to macráfolos, that are
mononuclear fagocitos, that along with the neutrófilos kill and ingest piógenas bacteria in individual. In the laboratory the potenciadora action of the tomentosa Uncaria has also been proven on the macrophages.
Antibacterial Therapy. - Harnessing the immunological system of defense the tomentosa Uncaria cure and in many cases stops a piógena disease. We have had the opportunity to observe this effect in children and adults suffering from infectious tonsilitis, in those who the treatment with tomentosa Uncaria eliminates the infection along with its sequels.
Antiviral therapy. - The virus is a nondetectable microorganism with the usual microscopes (2000 increases), if it is it with the electron microscope (1 000 000 increases). The virus gives rise enfermedades(virales): neumonía atypical primary, measles, varicela, rubeola, yellow fever, hepatitis, herpes, influenza, resfriado common. We remembered that a high degree of personal immunity regulates its development and in some cases its treatment;
to aciclovir, interferon gammaglobulina, and better than all these, its prevention by early specific vaccine administration, that grants to the man permanent or fleeting immunity according to the case. By means of the use of
first, during many decades it has been obtained the eradication of the smallpox and the poliomielitis.
In general, the antiviral action is exerted: a) Inhibiting the replication of the virus; and b) Stimulating the fagocitaria action.
Antineoplásica Therapy
There is in the human no organ nor woven body that cannot be attacked by the cancer, its etiología completely it is not explained, it is only known that there is one uncontrolled multiplication of cells, as much in weaves
like in the blood. The modern therapy consists of first term surgery of extirpation of the formed tumor, soon chemotherapy (oncológicos products) and x-ray. (Cobalt Pump).
Today it is a disease that is detected on time: Papanicolao (uterine cancer) and biopsies for the other forms of cancer. A numerous medicinal, oncofármacos product group exists for its treatment, very
expensive and that produces damage in the patient; every time they increase the possibilities of treatment, mainly when the diagnosis is precocious.
The development of the disease is enough complex, is not known exactly if mechanism but tacitly accepts the participation of oncovirus. Having the account that the tomentosa Uncaria of a side is
inmunoestimulante medicine) having knowledge of the anticancerous application that the native ones of the forest give him, is tried to apply it in the treatment, of this disease, and thus we expose next
versions of distinguished Peruvian doctors who study it and apply in clinic.
The Dr Mirez Melgarejo, in its work "Fitoterapia médica" carried out presented/displayed in 1988 in a Symposium, the Hospital Edgardo express Rebagliati: "Hemos successfully treated cancer about cervix, stomach suck, lung,
páncreas, ovary, prostate linfomas, rabdomasarcoma and leukemia, but in many cases we have seen necessary if participation in the treatments radioterápico and quimioterápico, also with good results; it express
in addition: use of the tomentosa Uncaria is an alternative in the treatment of the advanced cancer, is natural discipline that is not against another one (the indicated ones) constituting its better helping one, does not present/display effects
collateral and in all the cases it shows a significant antineoplásico effect evidently. The best results were obtained in cancer of: prostate, linfomas, breasts, ovaries, stomach rabdomosarcoma, and leukemia.
The Dr Jorge Aguilar Calderón ex- Dean of the Medicine Faculty of the National University Federico Villarreal, Peruvian scientist dedicated to revalue the natural medicine, is another one of the professionals of the health that
it drives the use of the cat nail, that in its concept fortifies the immunological system.
The Dr William Smitt, Director of the Peruvian Institute of Andean Fitoterapia (IPIFA) declares to the Commerce: "No we think that the medicinal plants are miraculous but we took advantage of the stimulating properties
of the tomentosa Uncaria on nonsingle the immunological system very appreciated in our country but abroad. It says in addition to have taken care of very many cases of cancer in the uterus, sucks, prostate stomach, lung etc., I want to leave in sure continues, that desire not to create exaggerated expectations, all the cases have not been cured, luckyly 80% have had improvement and what better quality of life is more important, I observed diminution of the pain and absence of collateral effects and if appeared some as you feel nauseous were minimum.
Galénicas Forms/Dosage
- Decocción: to 2% during 20 minutes. Three or more cups to the day.
- Dye (1:1º in alcohol solution 70º): 50-100 drops, one to three times to the day.
Bibliography
Obregón, HIM. Cat's claw "Uña of gato". Lima: Institute of Andean Fitoterapia, 1995, 144 pp.
Obregón, HIM. Studies on the "nail of cat" (tomentosa Uncaria). Natura Medicatrix, 1995; (37-78): 72-9.
ProductosList of Products of HIPERnatural.COM with :
Productos
Add to Favorite
