Name


Scientific Name

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Used Part

The leaves.

Active Principles

Alkaloids derived from the tropano, in smaller proportion than the belladona (0,20-0,45%): hiosciamina, atropine, escopolamina (more of 33% of the total alkaloids), norescopolamina.

Farmacológica Action

The atropine and the hiosciamina have a parasimpaticolítica action: antispasmodic, antiasthmatic, midriática, cardioaceleradora (although to low doses bradicardia causes one paradoxical), it elevates of moderate form the arterial tension, by increase of the peripheral resistance. The gastrointestinal peristaltismo diminishes. It produces a paralysis of uréteres. The gastric, pancreática, sudoral secretion diminishes and to salivar. The atropine is broncodilatadora (nevertheless it does not inhibit the production of broncoespasmos of histamínico origin). It is the analgesic premises. The escopolamina, more abundant alkaloid in estramonio, has sedative action on the central nervous system, considering itself like antiparkinsoniano.

Indications

It was used like antiparkinsoniano, antispasmodic and like the analgesic premises.

Due to the high toxicity of the alkaloids that contains, he is preferable not to use it in alopáticas doses.

Precaution/Poisonings

All the plant is toxic, with action similar, but more violent, than the belladona.

In low doses the poisoning attends with somnolencia, alterations of the vision, loss of sensitivity. To greater doses: cólicos pains, extreme midriasis, hallucinations, delirium and vertigos.

Bibliography

Benigni, R; Capra, C; Cattorini, P. Piante Medicinali. Chimica, Farmacologia and Terapia. Milano: Inverni & Della Beffa, 1962, pp. 1526-38.

Bézanger-Beauquesne, L; Pinkas, M; Torck, M. You plant dans to Them the Therapeutique Moderne. 2ª. Paris: Maloine, 1986, pp. 186-7.

Bézanger-Beauquesne, L; Pinkas, M; Torck, M; Trotin, F. Plantes Médicinales DES Regions Tempérées. Paris: Maloine, 1980, pp.288-9

British Herbal Pharmacopoeia. Vol. I. Bournemouth, Dorset: British Medical Herbal Association, 1990, p. 82.

Bruneton, J. Elementos de Fitoquímica and Farmacognosia. Zaragoza: Acribia, 1991, pp. 377-9.

D'Arcy, PF. Adver reactions and interactions with herbal medicine. Part I. Adver reactions. Adver Drug React Toxicol Rev, 1991; 10 (4): 189-208.

James, A; Duke, Ph D. Handbook of Medicinal Herbs. 5ª. Mouth Mouse, Florida: CRC Press, 1987, pp. 161-2; 240; 496; 519; 553.

Fernandez, M; Grandson, To Plantas Medicinal. Pamplona: Editions University of Navarre, 1982, p. 71.

Him Floc'h, And Contribution to unites Etude Ethnobotanique of the Flore Tunisienne. Imprimerie Officielle of the République Tunisienne, 1983, p. 225.

Mulet, L. toxic Flora of the Valencian Community. Castellón: Provincial delegation, 1997, pp. 159-62.

Nogué, S. Intoxicacio'n by plants, animal mushrooms and punctures. In: Farreras Rozman, Internal Medicine, 13ª (edition in D-ROM), Barcelona: Doyma, 1996, p. 2617.

Paris, RR; Moyse, M. Précis de Matière Médicale. Take III. Paris: Masson, 1971, pp. 158-64; 174.

Peris, JB; Stübing, G; Vanaclocha, B. Applied Fitoterapia. Valencia: M.I. Official school of Phamacists, 1995, pp. 270-1.

Peris, JB; Stübing, G; Figuerola, R. Gui'a of Plantas Medicinal of the Valencian Community. Valencia: The Provinces, 1996, p. 297.

Creek, D; Obón, C. Gui'a Incafo of Plantas Useful and Poisonous of the Iberian Peninsula and Baleares. Madrid: Incafo, 1991, pp. 805-6.

Real Spanish Farmacopea. Madrid: Ministry of Health and Consumption, 1997, pp. 877-9.

Samuelsson, G. Drugs of Natural Origin. To Textbook of Pharmacognosy. Stockholm: Swedish Pharmaceutical Press, 1992, p. 252.

Simón, R. Gui'a de Farmacologi'a for Phamacists and Doctors. Madrid: To Madrid Vicente, 1993, p. 21.

Trease, GE; Evans, WCh. Farmacognosia. Mexico D.F.: Inter-American -- MacGraw-Hill, 1991, pp. 602-8.

Hellemont, J. Compendium de Phytotherapie go. Bruxelles: Association Pharmaceutique Belge, 1986, pp.130-2.

Villar, L; Palacín, JM; Bald, C; Go'mez, D; Montserrat, G. Plantas Medicinal of the Pyrenean oscenses Aragonese and others tierrras. 2ª. Huesca: Provincial delegation, 1992, p. 260.


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