Antraquinónicos derivatives, in small proportion, antraquinonas mainly free, between which it emphasizes reína. Estigmasterol. Triptófano.
Farmacológica Action
Antraquinonas confers colerética and laxative an activity to him smooth, but effective. To high doses it acts like laxative.
Indications
Specially it is indicated to fight the occasional constipation in old children and.
Contraindications
Acute abdomen, intestinal obstruction. Pregnancy (by the oxitócico effect of the antracénicos derivatives), lactancia (when happening to maternal milk it can cause diarreas in the suckling babies), smaller children of six years. Intestinal or uterine menstruation, inflammatory states, cystitis. Hemorroides (it is irritating, although frequently an indication when causing is considered the defecación and reducing the pressure on the hemorroidal package). Hepática, renal or cardiac insufficiency, treatment with cardiotónicos (hipopotasemia can harness its action).
Indirect effect
Overdoses or their use in people with a greater sensitivity to the drug, can produce intestinal cólicos and vomits.
Precaution/Poisonings
The chronic ingestion of antraquinónicos derivatives can lead to the destruction of the nervous plexos intramurals of the colon, causing the denominated cathartic colon: a atónico and lacking heavy intestine of haustras, tubular aspect similar to the one of the ulcerosa colitis long play. Frecuentemante is accompanied by rectocólica melanosis. The abuse of laxatives can also determine diselectrolitemia - hipopotasemia is specially dangerous in cardiologists -, slight esteatorrea and losing enteropatía of proteins.
For the treatment of the chronic or habitual constipation, we recommended to resort to the mechanical laxatives, and to introduce the necessary moficicaciones in the diet and the habits.
Galénicas Forms/Dosage
Except for facultative prescription, not to take than three days followed more.
- Infusion: 10 g/litro. 1 cup before lying down. In necessary case, another cup in uninformed can be taken.
- Pulp of the fruit: 4 to 8 g, acts like laxative. 30 or more grams, like laxative.
- dry Extract (5:1): 250 to 800 mg/día (1 g is equivalent to 5 g of dry plant).
Bibliography
Bézanger-Beauquesne, L; Pinkas, M; Torck, M. You plant dans to Them the Therapeutique Moderne. 2ª. Paris: Maloine, 1986, p. 122.
Bruneton, J. Elementos de Fitoquímica and Farmacognosia. Zaragoza: Acribia, 1991, p. 213.
James, A; Duke, Ph D. Handbook of Medicinal Herbs. 5ª. Mouth Mouse, Florida: CRC Press, 1987, p. 102.
Fernandez, M; Grandson, To Plantas Medicinal. Pamplona: Editions University of Navarre, 1982, p. 54.
Gupta, MP. 270 Plantas Medicinal Latin American. Santafé of Bogota: Latin American program of Science and technology for Desarrollo (CYTED), 1995, pp. 353-5.
Paris, RR; Moyse, M. Précis de Matière Médicale. Take II. Paris: Masson, 1967, p. 366.
Peris, JB; Stübing, G; Vanaclocha, B. Applied Fitoterapia. Valencia: M.I. Official school of Phamacists, 1995, p. 194.
Hellemont, J. Compendium de Phytotherapie go. Bruxelles: Association Pharmaceutique Belge, 1986, pp. 88-9.