GREATER CELANDINE (chelidonium majus)

	G
	GREATER CELANDINE
	*chelidonium majus*

Name
GREATER CELANDINE

Scientific Name
chelidonium majus

GREATER CELANDINE

Latin: Chelidonium majus L.

Castilian: celandine, celidueña, verruguera, grass of the wanderers, grass of warts

English: celandine, chelandine, tetterwort.

Of the family of the Papaveráceas.

It does not have to be used internally by its toxicity.

External use: látex serves to cauterize warts.

Used Part

The flowery sumidades. Látex fresh.

Active Principles

Alkaloids of bencilisoquinoleínico type (0,1-0,5%): quelidonina, sanguinarina, queleritrina, protopina, berberina, coptisina, estilopina. Quelidónico Acido. Flavonoides. Saponósidos. Carotenoid. In látex: proteolytic enzymes.

Farmacológica Action

The celidonina is espasmolítica, analgesic, slightly sedative, Antitusiva, antiviral. The berberina is colagoga. The coptisina is queratolítica and antimitótica, reason why it is used like antiverrucosa. Some alkaloids present/display a antibacterial action.

Indications

Espasmos of the respiratory tree: biliary laringospasmos, broncospasmos, cough, dismenorreas, jaquecas, disquinesias, colecistitis, colelitiasis. In topical application it is used to treat the hiperqueratosis, corneous warts, condilomas and papilomas.

Contraindications

Pregnancy, lactancia, obstruction of the biliary routes (oral route).

Not to apply on nevus.

Precaution/Poisonings

By the abundance of alkaloids its use is not recommendable internally. It can cause narcosis, paralysis of the sensitive nervous completions, bradicardia and contracturas tetánifomes. It is considered that its administration of continued form can be oncogénica. In any case, we recommended, to prescribe short treatments, without surpassing the indicated doses.

One has described a case of anemia with intravascular hemólisis, renal failure, hepática citolisis and trombocitopenia after the oral ingestion of a celandine extract (Peris ET to, 1997).

Látex is dermocáustico, very irritating of the skin and the mucous.

Galénicas Forms/Dosage

Internal use:

- Infusion: 10 g/litro. To instill 10 minutes, one to three cups to the day.

- Dust: 200-300 mg/día.

- fluid Extract (1:1): 10-20 drops, one or twice to the day.

- It tinctures (1:5): 30-50 drops, one to three times to the day.

- dry Extract (5:1): 50-100 mg, one or twice to the day

Topical use:

- To rub warts two or three times to the day with látex fresh. To apply with gloves, protecting the surrounding zones with filante petroleum jelly.

- fluid Extract and glycerin to equal parts, like corn remover. To apply at night, after pediluvio warms up.

Bibliography

Benigni, R; Capra, C; Cattorini, P. Piante Medicinali. Chimica, Farmacologia and Terapia. Milano: Inverni & Della Beffa, 1962, pp. 276-82.

Bézanger-Beauquesne, L; Pinkas, M; Torck, M. You plant dans to Them the Therapeutique Moderne. 2ª. Paris: Maloine, 1986, pp. 131-2.

Bézanger-Beauquesne, L; Pinkas, M; Torck, M; Trotin, F. Plantes Médicinales DES Regions Tempérées. Paris: Maloine, 1980, pp.116-7.

Bruneton, J. Elementos de Fitoquímica and Farmacognosia. Zaragoza: Acribia, 1991, p. 437.

D'Arcy, PF. Adver reactions and interactions with herbal medicine. Part II. Drug interactions. Adver Drug React Toxicol Rev, 1993; 12 (3): 147-162.

James, A; Duke, Ph D. Handbook of Medicinal Herbs. 5ª. Mouth Mouse, Florida: CRC Press, 1987, p. 113.

Fernandez, M; Grandson, To Plantas Medicinal. Pamplona: Editions University of Navarre, 1982, p. 58.

It ballast, JJ; Bachelor, LI. Medicinal plants in Asturias and the Cantabrian Cornice. Gijón: Trea editions, 1997, pp. 106-7.

Mulet, L. Estudio Etnobotánico of the Province of Castellón. Castellón: Provincial delegation, 1991, p. 114.

Mulet, L. toxic Flora of the Valencian Community. Castellón: Provincial delegation, 1997, pp. 112; 129-131.

Paris, RR; Moyse, M. Précis de Matière Médicale. Take II. Paris: Masson, 1967, pp. 207-8.

Peris, JB; Stübing, G; Vanaclocha, B. Applied Fitoterapia. Valencia: M.I. Official school of Phamacists, 1995, pp. 211-2.

Peris, JB; Stübing, G; Figuerola, R. Gui'a of Plantas Medicinal of the Valencian Community. Valencia: The Provinces, 1996, p. 242.

Hellemont, J. Compendium de Phytotherapie go. Bruxelles: Association Pharmaceutique Belge, 1986, pp. 96-7.

Villar, L; Palacín, JM; Bald, C; Go'mez, D; Montserrat, G. Plantas Medicinal of the Pyrenean oscenses Aragonese and others tierrras. 2ª. Huesca: Provincial delegation, 1992, p. 82.

Wichtl, M. Herbal Drugs and Phytopharmaceutical. To for Handbook Practice on to Scientific basis. Stuttgart: Medpharm Scientific Publishers, 1994, pp. 143-5.

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