DISEASE DE JACOB CREUTZFELDT

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	DISEASE DE JACOB CREUTZFELDT
	*DISEASE DE JACOB CREUTZFELDT*

DISEASE DE JACOB CREUTZFELDT

Disease of Jacob Creutzfeldt

An infection produced by priones, infectious protein particles of recent recognition. He is contagious by direct bonding with infected weaves, and possibly by ingestion. A variant produces the "Disease of the crazy cows" in the man. Near 15 % of the cases they are familiar.

Causes

Contact or product ingestion of the infected central nervous system.

Other sources of I infect are more doubtful and object of intense studies.

Signs and symptoms

The patients quickly present/display a progressive dementia with mioclonías (repeated contractions of small muscular groups).

Initially they can appear:

Slow thought,

Difficulty to concentrate itself,

Loss of memory and

Loss of judgment.

At the end of the disease when advancing the dementia:

Changes of humor,

Hallucinations and, finally, dementia.

Factors of risk

Contact with weaves of nervous system (Transplants of cornea or injections of pituitaria). Neuroquirúrgicos procedures.

The transmission of the "Disease of the crazy cows" has been demonstrated to the humans, but the concrete risk is object of great debate.

Prevention

To avoid, as far as possible, the risk factors.

It is difficult to detect in nervous weaves the presence of the disease, or the infectividad of such.

Diagnosis and treatment

Sanitary precautions

Medical treatment.

Psycotherapy or advising to help him to live with a incurable disease.

Chemotherapy and/or therapy of radiation.

Surgery stops:

To extirpate the tumor, when he is small.

To mitigate any pressure in the biliary conduits.

To mitigate or to avoid obstructions in vejiga.

Systems of diagnosticos

Observation of the symptoms.

File and physical examination by its doctor.

Analysis of blood.

The tests of imaginería (TAC and RMI) provide a diagnosis of presumption when being appraised a quickly progressive atrophy of the cerebral structures.

EEG (Electroencefalograma) presents/displays a typical pattern in many cases, which aid in the diagnosis.

Definitive the diagnóstica test is the microscopic study of a cerebral weave sample obtained by biopsy or in the autopsy.

Complications

The derived ones from the deterioration of the cerebral functions (traumatismos, infections, malnutrición...)

Prognosis

It does not exist.

Unlucky. The disease is mortal.

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