PERNICIOUS ANEMIA (DEFICIENCY B12 VITAMIN)

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	PERNICIOUS ANEMIA (DEFICIENCY B12 VITAMIN)
	*PERNICIOUS ANEMIA (DEFICIENCY B12 VITAMIN)*

PERNICIOUS ANEMIA (DEFICIENCY B12 VITAMIN)

Pernicious anemia (DEFICIENCY B12 VITAMIN)

The lack of red globules caused by deficiency B12 the vitamin.

Deficiency B12 the vitamin also affects to other weaves with high rates of spare part.

Sex

It affects mainly to the adults between the 50 and 60 years of age.

Rare in children.

Prognosis

At the present time, this disease is incurable.

Nevertheless, consumption the regular B-12 vitamin will control the symptoms indefinitely and will correct the complications.

Once begun the treatment, the symptoms can disappear in 6 months.

Causes

Absence of the intrinsic factor, a chemical agent secreted by the mucosa of the membrane of the stomach, that facilitates the absorption of the B-12 vitamin.

The reason for the absence of the intrinsic factor is not known, although a genetic deficiency or a disease can be due to autoinmune.

Reduction of the hydrochlorate acid production, specially after a combined operation of stomach or with the lack of the intrinsic factor (the hydrochlorate acid is equally necessary for the absorption of the B-12 vitamin).

Signs and symptoms

Weakness, specially in arms and legs.

Escocida language.

Nauseas, loss of appetite and weight.

Encías bleeding.

Entumecimiento and creeps in hands and feet.

Difficulty to conserve the balance.

Lips, pale language and encías.

Yellowish eyes and skin.

Difficult breathing.

Depression.

Confusion and dementia.

Migraines.

Losses of memory.

Factors of risk

An inadequate diet, specially the vegetarians without supplements B12 vitamin.

Affection of the thyroid.

Previous operation of stomach, cancer of stomach or gastritis.

Bulimia or nervous anorexy.

Familiar antecedents of pernicious anemia.

Genetic factors. This disease is common in the north of rare Europe and in the races black and Asian.

Prevention

If it has been operated of the stomach or if it suffers of gastritis, B-12 vitamin must be injected with regularity.

Diagnosis and treatment

DIAGNOSIS:

File and physical examination by a doctor.

Analysis of blood.

Specific studies, like the determination of concentration B12 the Vitamin in the blood or the Test of Schilling with radioactive B-12 vitamin.

Analysis of the bony marrow.

TREATMENT:

General measures

Avoid the very hot water and the hot compresas.

Its nervous system could be incapable to detect the dangerously high temperatures.

Medication

His doctor will prescribe injections to him B-12 vitamin. The power and frequency of the same ones will depend on the importance of the disease.

The usual dose is of a daily injection during 7 days, later a weekly injection during a month and an injection to the month during the rest of their life.

Learn to inject the B-12 vitamin, since the oral supplements are not enough.

The treatment of by life is essential since, still with treatment, its capacity of absorption of vitaminaB-12 will not be the normal one.

Activity

Without restrictions.

Diet

No special one.

No longer the crude meat nor the liver are recommended.

The iron supplements can be necessary.

Warn its medico if

The symptoms do not improve to the 2 weeks of treatment.

Complications

Congestivo cardiac failure.

Double vision.

Greater susceptibility to the infections.

Masculine impotence.

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